Clinical data

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Trisomy

Trisomy

Trisomy

Trisomies

Trisomy

T21
T18
T13
Total

Detection rate

99.17%

98.24%

100%

99.02%

Specificity

99.95%

99.95%

99.96%

99.86%

Positive predictive value (PPV)

92.19%

76.61%

32.84%

85.27%

Negative predictive value (NPV)

99.99%

100%

100%

99.99%

Positioning statements and guidelines regarding NIPT

October 2012

International Society for Prenatal Diagnosis ISPD

Prenat Diagn 2012;32:1-2

June 2012

Association of Privately Practising Prenatal Medical Professionals BVNP

November 2012

German Human Genetics Society GfH

December 2012

The American College of Obstetricians and Gynecologists Committee on Genetics and The Society for Maternal-Fetal Medicine Publications Committee ACOGP

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